Mouse Anti-Human LTB (C-term)(Ascites) Antibody, 0.1 ml
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Product Description
Specifications
| Size | 0.1 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | Q06643 |
| Gene Id | 4050 |
| Gene Symbols | LTB |
| Protein Name / Synonyms | LTB (C-term)(Ascites) |
| Clonality | Monoclonal |
| Preparation | This LTB antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the C-terminal region of human LTB. |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specificity
Predicted Reactivity
Pig
Other Names
LTB; TNFC; TNFSF3; Lymphotoxin-beta; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3
NCBI Accession #
NP_002332.1;NP_033666.1
Other Accession #
Q9TSV8; NP_033666.1; NP_002332.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
25390
Recommended Dilutions
WB: 1:2000-16000
 | LTB Antibody (C-term) (Cat# 102-10243) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LTB antibody detected the LTB protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
