Rabbit Anti-Human MCA1 (C-term) Antibody, 400 ul
Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q12904 |
| Gene Id | 9255 |
| Gene Symbols | AIMP1 |
| Protein Name / Synonyms | MCA1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This MCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the C-terminal region of human MCA1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
MCA1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
Specificity
Predicted Reactivity
Mouse, Hamster
Other Names
AIMP1; EMAP2; SCYE1; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; Multisynthase complex auxiliary component p43; Endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; Small inducible cytokine subfamily E member 1
NCBI Accession #
NP_001135887.1;NP_001135888.1;NP_004748.2
Other Accession #
P31230; O54873
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
34353
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of MCA1 antibody (C-term) (Cat# 102-16909) in 293 cell line lysates (35ug/lane). MCA1 (arrow) was detected using the purified Pab. |
 | Western blot analysis of MCA1(arrow) using rabbit polyclonal MCA1 Antibody (N-term) (Cat# 102-16909). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MCA1 gene (Lane 2) (Origene Technologies). |
 | MCA1 Antibody (C-term) (Cat# 102-16909) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCA1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.