Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P98177 |
| Gene Id | 4303 |
| Gene Symbols | FOXO4 |
| Protein Name / Synonyms | MLLT7 (N-term) |
| Clonality | Polyclonal |
| Preparation | This MLLT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human MLLT7. |
| Concentration (lot specific) | 0.400 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The MLLT7 (Mixed-lineage leukemia translocated to 7) protein is a forkhead transcription factor that activates apoptosis by inducing the BCL-6 transcriptional repressor. MLL-MLLT7 fusion protein transformw myeloid progenitors and impairs forkhead protein function. MLLT7 is a target of the phosphatidylinositol 3-kinase/PKB insulin signaling pathway and the AMP-activated protein kinase-dependent pathway.
Specificity
Other Names
FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1
NCBI Accession #
NP_001164402.1;NP_005929.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
53684
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | MLLT7 Antibody (R59) (Cat# 102-16672) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MLLT7 antibody detected the MLLT7 protein (arrow). |
 | MLLT7 antibody (N-term) (Cat# 102-16672)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MLLT7 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.