Product Description

Specifications

Size	20 µg, 100 µg, 200 µg, 500 µg
Estimated Lead Time	1-2 business days
Species	Mouse
Accession Number	AY217100
Clonality	Polyclonal
Immunogen	This antibody was produced from a rabbit immunized with the KLH-conjugated peptide derived from human Mammglobin as immunogen. The IgG fraction (lyophilized antibody) of immunized serum was purified by affinity chromatography.
Recommended Applications	ELISA (recommended work dilution= 1:10e4), Western Blotting (recommended work dilution= 1:500-1000)
Reconstitution	Supplied as lyophilized purified antibody. The antibody is stable for at least a few years from the data of receipt when stored at -20°C to -70°C. Reconstituted antibody (recommended with H20 1 mg/ml) can also be aliquoted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss activity. Upon reconstitution, the antibody can be stored at 4°C for 1 month. If 1 ml of H20 is used, the antibody concentration will be 100 µg/ml. Please avoid freeze-thaw cycles.
Research Area	Cardiovascular Disease
Shipping Type	Ambient temperature
Storage	-20°C

Description

Mammaglobin (MAM) is a member of the secretoglobin superfamily, which also includes uteroglobin (Clara cell protein; Clara cell 10 kDa protein), lymphoglobin, and the lipophilins A, B (BU101), and C (lacryglobin; mammaglobin B). In human breast tissue, mammaglobin is secreted as a glycosylated peptide, which is covalently associated with lipophilin B. Mammaglobin, a mammary-specific member of the uteroglobin family, is known to be overexpressed in human breast cancer. It has been used as a specific molecular marker for breast cancer diagnosis. Mammaglobin is expressed mainly by breast epithelial cells, and this feature has been used to detect circulating breast cancer cells and occult metastases in sentinel axillary lymph nodes of breast cancer patients.

Specificity

The antibody detects specifically target derived from human protein by ELISA and Dot Blotting. Cross reactivity with mouse and rat are not tested yet.

Storage

Store at -20°C, if not intended for use within a month, Keep it at 4°C and minimize freezing and thawing when use.

References

Alvarez, J, Vinas, J, Alonso, JM, Albar, JP, Ashman, K, Dominguez, P: Characterization and cloning of two isoforms of heteroglobin, a novel heterodimeric glycoprotein of the secretoglobin-uteroglobin family showing tissue-specific and sex differential expression. J Biol Chem 2002 233242,
Carter, D, Douglass, JF, Cornellison, CD, et al: Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer. Biochemistry 2002 41: 67146722,

Expiration:

12 months from the date of shipment when stored properly.

Description

Specificity

The antibody detects specifically target derived from human protein by ELISA and Dot Blotting. Cross reactivity with mouse and rat are not tested yet.

Storage

Store at -20°C, if not intended for use within a month, Keep it at 4°C and minimize freezing and thawing when use.

References

Alvarez, J, Vinas, J, Alonso, JM, Albar, JP, Ashman, K, Dominguez, P: Characterization and cloning of two isoforms of heteroglobin, a novel heterodimeric glycoprotein of the secretoglobin-uteroglobin family showing tissue-specific and sex differential expression. J Biol Chem 2002 233242,
Carter, D, Douglass, JF, Cornellison, CD, et al: Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer. Biochemistry 2002 41: 67146722,

Expiration:

12 months from the date of shipment when stored properly.

Anti-Mouse Mammaglobin Antibody

Anti-Mouse Mammaglobin Antibody

Product Description

Specifications

Description

Specificity

Storage

References

Anti-Mouse Mammaglobin Antibody

Anti-Mouse Mammaglobin Antibody

Product Description

Specifications