Rabbit Anti-Mouse PDE8B (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | O95263 |
| Gene Id | 8622 |
| Gene Symbols | PDE8B |
| Protein Name / Synonyms | PDE8B (Center) |
| Clonality | Polyclonal |
| Preparation | This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Specificity
Other Names
PDE8B; High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; Cell proliferation-inducing gene 22 protein
NCBI Accession #
NP_001025022.1;NP_001025023.1;NP_001025024.1;NP_001025025.1;NP_003710.1
Other Accession #
E9Q4S1; NP_003710.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
98979
Recommended Dilutions
WB: 1:1000
 | PDE8B Antibody (Center) (Cat# 102-14518) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PDE8B antibody detected the PDE8B protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
