Rabbit Anti-Natriuretic Peptide Receptor A (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P16066 |
| Gene Id | 4881 |
| Gene Symbols | NPR1 |
| Protein Name / Synonyms | Natriuretic Peptide Receptor A (N-term) |
| Clonality | Polyclonal |
| Preparation | This Natriuretic Peptide Receptor A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Natriuretic Peptide Receptor A. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | IHC-P |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.
Specificity
Other Names
NPR1; ANPRA; Atrial natriuretic peptide receptor 1; Atrial natriuretic peptide receptor type A; Guanylate cyclase A
NCBI Accession #
NP_000897.3
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
118919
Recommended Dilutions
IHC: 1:10-50
 | Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Natriuretic Peptide Receptor A (NPR1/ANPA) antibody (N-term) (Cat# 102-17808), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.