Rabbit Anti-Human NUMB (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49757 |
| Gene Id | 8650 |
| Gene Symbols | NUMB |
| Protein Name / Synonyms | NUMB (N-term) |
| Clonality | Polyclonal |
| Preparation | This NUMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NUMB. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
NUMB; Protein numb homolog; Protein S171
NCBI Accession #
NP_001005743.1;NP_001005744.1;NP_001005745.1;NP_003735.3
Other Accession #
Q2LC84; Q9QZS3; NP_003735.3; NP_001005743.1; NP_001005745.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
70804
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | NUMB Antibody (N-term) (Cat# 102-11099) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NUMB antibody detected the NUMB protein (arrow). |
 | NUMB Antibody (N-term) (Cat# 102-11099)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NUMB Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.