Rabbit Anti-Human PGR/PR (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P06401 |
| Gene Id | 5241 |
| Gene Symbols | PGR |
| Protein Name / Synonyms | PGR/PR (C-term) |
| Clonality | Polyclonal |
| Preparation | This PGR/PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human PGR/PR. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | IF, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
Specificity
Other Names
PGR; NR3C3; Progesterone receptor; Nuclear receptor subfamily 3 group C member 3
NCBI Accession #
NP_000917.3;NP_001189403.1;NP_001258091.1
Other Accession #
NP_000917.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
98981
Recommended Dilutions
IF: 1:10-50; WB: 1:1000
 | Fluorescent image of U251 cell stained with PGR/PR Antibody (C-term)(Cat# 102-14207).U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with PGR/PR primary antibody (1:25, 1 h at 37°). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°).PGR/PR immunoreactivity is localized to Nucleus significantly and Vesicles weakly. |
 | PGR/PR Antibody (C-term) (Cat# 102-14207) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PGR/PR antibody detected the PGR/PR protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.