Rabbit Anti-Human PSEN2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49810 |
| Gene Id | 5664 |
| Gene Symbols | PSEN2 |
| Protein Name / Synonyms | PSEN2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PSEN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from the N-terminal region of human PSEN2(Presenilin-2 NTF subunit). |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Specificity
Other Names
Presenilin-2, PS-2, 3423-, AD3LP, AD5, E5-1, STM-2, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit, PSEN2, AD4, PS2, PSNL2, STM2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
50140
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of lysate from Hela cell line, using PSEN2(Presenilin-2 NTF subunit) Antibody (N-term)(Cat# 102-14953). 102-14953 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.