Rabbit Anti-Human PUF60 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UHX1 |
| Gene Id | 22827 |
| Gene Symbols | PUF60 |
| Protein Name / Synonyms | PUF60 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PUF60 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human PUF60. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Specificity
Other Names
PUF60; FIR; ROBPI; SIAHBP1; Poly(U)-binding-splicing factor PUF60; 60 kDa poly(U)-binding-splicing factor; FUSE-binding protein-interacting repressor; Ro-binding protein 1; Siah-binding protein 1
NCBI Accession #
NP_001129505.1;NP_001258025.1;NP_001258026.1;NP_001258027.1;NP_001258028.1;NP_001258029.1;NP_055096.2;NP_510965.1
Other Accession #
NP_510965.1; NP_055096.2; NP_001129505.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
59875
Recommended Dilutions
WB: 1:1000
 | PUF60 Antibody (N-term) (Cat# 102-12457) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PUF60 antibody detected the PUF60 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.