Rabbit Anti-SRRT (N-term) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9BXP5|Q99MR6|A4IFB1|NP_001122325.1|NP_001122324.1 |
| Gene Id | 51593 |
| Gene Symbols | SRRT |
| Protein Name / Synonyms | Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, SRRT, ARS2, ASR2 |
| Clonality | Polyclonal |
| Clone | RB37036 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
SRRT acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.
Other Information
NCBI Accession #
NP_001122324.1;NP_001122325.1;NP_001122326.1;NP_056992.4
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
100666
Antigen Source
Human
Images
WB (1:1000)
SRRT Antibody (N-term) (Cat. #102-22657) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SRRT antibody detected the SRRT protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.