Rabbit Anti-Human STAT2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P52630 |
| Gene Id | 6773 |
| Gene Symbols | STAT2 |
| Protein Name / Synonyms | STAT2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This STAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the N-terminal region of human STAT2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Specificity
Predicted Reactivity
Pig
Other Names
STAT2; Signal transducer and activator of transcription 2; p113
NCBI Accession #
NP_005410.1;NP_938146.1
Other Accession #
O02799; NP_005410.1; NP_938146.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
97916
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | STAT2 Antibody (N-term) (Cat# 102-12137) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the STAT2 antibody detected the STAT2 protein (arrow). |
 | STAT2 Antibody (N-term) (Cat# 102-12137)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STAT2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.