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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Accession Number | P20226 |
| Gene Id | 6908 |
| Gene Symbols | TBP |
| Protein Name / Synonyms | TBP |
| Clonality | Monoclonal |
| Preparation | Purified His-tagged TBP protein was used to produced this monoclonal antibody. |
| Concentration (lot specific) | 0.370 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Specificity
Other Names
TBP;GTF2D1; TF2D; TFIID; TATA-box-binding protein; TATA-box-binding protein; TATA sequence-binding protein; TATA-box-binding protein; TATA-binding factor; TATA-box-binding protein; TATA-box factor; TATA-box-binding protein; Transcription initiation factor TFIID TBP subunit
NCBI Accession #
NP_001165556.1;NP_003185.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
37698
Recommended Dilutions
WB: 1:1000
 | TBP Antibody (Cat# 102-10412) western blot analysis in Hela,HepG2,mouse NIH/3T3 cell line lysates (35ug/lane).This demonstrates the TBP antibody detected the TBP protein (arrow). |
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
