Rabbit Anti-Human TOP1 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P11387 |
| Gene Id | 7150 |
| Gene Symbols | TOP1 |
| Protein Name / Synonyms | TOP1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This TOP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human TOP1. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IF |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Specificity
Predicted Reactivity
Mouse, Rat, Hamster
Other Names
TOP1; DNA topoisomerase 1; DNA topoisomerase I
NCBI Accession #
NP_003277.1
Other Accession #
Q9WUL0; Q04750; Q07050; NP_003277.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
90726
Recommended Dilutions
WB: 1:1000; IF: 1:10-50
 | TOP1 Antibody (N-term) (Cat# 102-12208) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TOP1 antibody detected the TOP1 protein (arrow). |
 | Confocal immunofluorescent analysis of TOP1 Antibody (N-term)(Cat# 102-12208) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.