Rabbit Anti-Human TTK (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P33981 |
| Gene Id | 7272 |
| Gene Symbols | TTK |
| Protein Name / Synonyms | TTK (N-term) |
| Clonality | Polyclonal |
| Preparation | This TTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human TTK. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
Specificity
Predicted Reactivity
Monkey
Other Names
TTK; MPS1; MPS1L1; Dual specificity protein kinase TTK; Phosphotyrosine picked threonine-protein kinase
NCBI Accession #
NP_001160163.1;NP_003309.2
Other Accession #
Q4R945; NP_003309.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
97072
Recommended Dilutions
WB: 1:1000
 | TTK Antibody (N-term) (Cat# 102-13316) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the TTK antibody detected the TTK protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
