Vascular endothelial growth factor (VEGF) is a member of the PDGF/VEGF growth factor family, produced by cells that stimulate the growth of new blood vessels. VEGF family includes VEGF-A, B, C, and D isoforms. VEGF-A was called VEGF before other isoforms were discovered. VEGF plays an important role in creating new blood vessels, inducing angiogenesis, vasculogenesis and endothelial cell growth, inhibiting apoptosis, mediating increased vascular permeability, promoting cell migration, etc. VEGF members stimulate cellular responses through binding to tyrosine kinase receptors (VEGFRs) on the cell surface.

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

The mouse anti-human VEGF antibody specifically detects targets derived from human recombinant protein at various concentrations. Cross reactivity with mouse and rat are expected from sequence similarity.