Fighting COVID-19

Most Comprehensive Selection in the World

Fighting the COVID-19 pandemic requires an arsenal of research tools and reagents. RayBiotech provides the most complete and comprehensive range of products and services to support your efforts in SARS-CoV-2 research and development of therapies and vaccines.

For researchers and health professionals needing lab facilities or additional expertise, RayBiotech offers contract research services to help reach your objectives faster. The Pipet symbol indicates products for which we offer full testing or custom service.

COVID-19 Collaborations: Collaborate with RayBiotech to advance COVID-19 research.


Antibody Testing

Antibody Screening Assays & ServicesPipet

Antibody screening has important public health uses in determining immunity to and prevalence of COVID-19, as well as identifying who has been infected and evaluating potential blood based therapeutics. Detect IgG, IgM, and IgA antibodies to SARS-CoV-2 N and S proteins using the indirect ELISA kits. Binding assays and pseudovirus services are available to determine if the antibodies present can inhibit cell binding, are neutralizing, or suitable for vaccine development.

COVID-19 Indirect ELISA

Antigen Testing

SARS-CoV-2 antigen immunoassays test for the presence of viral proteins directly (unlike antibody tests, which detect an immune response to the virus). Highly sensitive ELISA and lateral flow assays are available for the nucleocapsid (N) and spike (S) proteins.

Antigen test schematic

Proteins

Recombinant SARS-CoV-2 Spike, Nucleocapsid, and Membrane proteins expressed in human, insect, and bacterial cells. Endogenous human and mouse proteins involved in SARS-CoV-2 infection also available, including ACE2, Neuropilin-1, and thrombrosis-related proteins.

COVID-19 Proteins SDS-PAGE

AntibodiesPipet

Monoclonal & Polyclonal Antibodies to SARS-CoV-2

COVID-19 Antibodies

ELISA KitsPipet

Detect IgG, IgM, and IgA antibodies to SARS-CoV-2 N and S proteins in serum, saliva, and dried blood samples using the indirect ELISA kits. Sandwich ELISA kits also available for detecting SARS-CoV-2 proteins (Spike, Nucleocapsid) and endogenous human proteins (ACE2, Neuropilin-1).

COVID-19 ELISA

PCRPipet

PCR Tests for SARS-CoV-2

RayBiotech's innovative PCR kits allow rapid, convenient detection of SARS-CoV-2 nucleic acids. Our protocols offer unique advantages, such as enabling the researcher to skip laborious RNA extraction, or to avoid PCR machines entirely, and detect the virus by visual color inspection.

Coronavirus PCR Test

Patient Samples

Different sample types from COVID-19 diagnosed patients and COVID-19 vaccinated patients, including serum/plasma, PBMCs, dried blood spots, & more. Serum/plasma from non-COVID-19 ("normal") patients also available.


Sample Collection Kits

Saliva and dried blood sample collection kits for RNA, DNA, Antibody and Protein analysis in normal (non-COVID-19) and COVID-19 samples.

PanoHealth blood collection kit

Aptamers

Anti-SARS-CoV-2 N-Protein Aptamer

Frequently referred to as "synthetic antibodies", aptamers are single stranded DNA molecules which can specifically recognize and bind to the targeted protein. Multiple modifications available. Aptamer selection was done against recombinant SARS-CoV-2 protein (cat# 230-30164).

COVID-19 Aptamer chemical structure

Inhibitor ScreeningPipet

Viral entry is mediated by interactions between the SARS-CoV-2 Spike protein and key host receptors. Due to the pivotal role that Spike plays in COVID-19 infection, the identification of inhibitors of Spike-receptor complexes will accelerate vaccine and drug development. RayBiotech offers ELISA-based COVID-19 binding assay kits for the high throughput, rapid screening of potential inhibitors in vitro. Inhibitors can also be analyzed in cell culture using our COVID-19 Pseudovirus Service.

ACE2 and SARS-CoV-2 Spike Protein Binding

Small Molecules / Inhibitors

Name Catalog # CAS # Target Candidate
Arbidol HCl 331-11756 131707-23-8 Viral spike glycoprotein for binding to host cell receptor ACE2
Ritonavir 331-11642 155213-67-5 HIV Protease
Lopinavir 331-11643 192725-17-0 Coronavirus main protease 3CLpro
Darunavir 331-11645 206361-99-1 HIV Protease
Ribavirin 331-10301 36791-04-5 RNA-dependent RNA polymerase
Chloroquine diphosphate 331-11962 54-05-7 Malaria (endosome/ACE2)
Nitazoxanide 331-11871 55981-09-4 Viral protein expression
Camostat mesilate 332-10779 59721-29-8 Transmembrane protease, serine 2, primes S protein to facilitate its binding to ACE2
Hydroxychloroquine Sulfate 331-21357 747-36-4 Malaria (endosome/ACE2)
Baricitinib Phosphate 332-10769 1187595-84-1 JAK kinase that regulate the inflammatory processes

Multiplex Protein ArrayPipet

Semi-quantitative detection of IgM and IgG antibodies in serum or plasma to the SARS-CoV-2 (COVID-19) spike (S) protein.

COVID-19 Array

Questions? Please contact [email protected] or at (888) 494-8555.

References:

  1. Li, W. et al. (2003) Nature 426:450.
  2. Hoffmann, M. et al. (2020) Cell. DOI: 10.1016/j.cell.2020.02.052.