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Fighting COVID-19
Most Comprehensive Selection in the World
Fighting the COVID-19 pandemic requires an arsenal of research tools and reagents. RayBiotech provides the most complete and comprehensive range of products and services to support your efforts in SARS-CoV-2 research and development of therapies and vaccines.
For researchers and health professionals needing lab facilities or additional expertise, RayBiotech offers contract research services to help reach your objectives faster. The 
symbol indicates products for which we offer full testing or custom service.
COVID-19 collaborations: collaborate with RayBiotech to advance COVID-19 research.
Tools for vaccine development: kits and reagents to accelerate your vaccine research.
Antibody Testing
Antibody Screening Assays & Services
Antibody screening has important public health uses in determining immunity to and prevalence of COVID-19, as well as identifying who has been infected and evaluating potential blood based therapeutics. Detect IgG, IgM, and IgA antibodies to SARS-CoV-2 N and S proteins using the indirect ELISA kits. Binding assays and pseudovirus services are available to determine if the antibodies present can inhibit cell binding, are neutralizing, or suitable for vaccine development.
Antigen Testing
SARS-CoV-2 antigen immunoassays test for the presence of viral proteins directly (unlike antibody tests, which detect an immune response to the virus). Highly sensitive ELISA and lateral flow assays are available for the nucleocapsid (N) and spike (S) proteins.
Proteins
Recombinant SARS-CoV-2 Spike, Nucleocapsid, and Membrane proteins expressed in human, insect, and bacterial cells. Endogenous human and mouse proteins involved in SARS-CoV-2 infection also available, including ACE2, Neuropilin-1, and thrombrosis-related proteins.
Antibodies
Monoclonal & Polyclonal Antibodies to SARS-CoV-2
ELISA Kits
Detect IgG, IgM, and IgA antibodies to SARS-CoV-2 N and S proteins in serum, saliva, and dried blood samples using the indirect ELISA kits. Sandwich ELISA kits also available for detecting SARS-CoV-2 proteins (Spike, Nucleocapsid) and endogenous human proteins (ACE2, Neuropilin-1).
PCR
PCR Tests for SARS-CoV-2
RayBiotech's innovative PCR kits allow rapid, convenient detection of SARS-CoV-2 nucleic acids. Our protocols offer unique advantages, such as enabling the researcher to skip laborious RNA extraction, or to avoid PCR machines entirely, and detect the virus by visual color inspection.
Patient Samples
Different sample types from COVID-19 diagnosed patients and COVID-19 vaccinated patients, including serum/plasma, PBMCs, dried blood spots, & more. Serum/plasma from non-COVID-19 ("normal") patients also available.
Sample Collection Kits
Saliva and dried blood sample collection kits for RNA, DNA, Antibody and Protein analysis in normal (non-COVID-19) and COVID-19 samples.
Aptamers
Anti-SARS-CoV-2 N-Protein Aptamer
Frequently referred to as "synthetic antibodies", aptamers are single stranded DNA molecules which can specifically recognize and bind to the targeted protein. Multiple modifications available. Aptamer selection was done against recombinant SARS-CoV-2 protein (cat# 230-30164).
Inhibitor Screening
Viral entry is mediated by interactions between the SARS-CoV-2 Spike protein and key host receptors. Due to the pivotal role that Spike plays in COVID-19 infection, the identification of inhibitors of Spike-receptor complexes will accelerate vaccine and drug development. RayBiotech offers ELISA-based COVID-19 binding assay kits for the high throughput, rapid screening of potential inhibitors in vitro. Inhibitors can also be analyzed in cell culture using our COVID-19 Pseudovirus Service.
Small Molecules / Inhibitors
| Name | Catalog # | CAS # | Target Candidate |
|---|---|---|---|
| Arbidol HCl | 331-11756 | 131707-23-8 | Viral spike glycoprotein for binding to host cell receptor ACE2 |
| Ritonavir | 331-11642 | 155213-67-5 | HIV Protease |
| Lopinavir | 331-11643 | 192725-17-0 | Coronavirus main protease 3CLpro |
| Darunavir | 331-11645 | 206361-99-1 | HIV Protease |
| Ribavirin | 331-10301 | 36791-04-5 | RNA-dependent RNA polymerase |
| Chloroquine diphosphate | 331-11962 | 54-05-7 | Malaria (endosome/ACE2) |
| Nitazoxanide | 331-11871 | 55981-09-4 | Viral protein expression |
| Camostat mesilate | 332-10779 | 59721-29-8 | Transmembrane protease, serine 2, primes S protein to facilitate its binding to ACE2 |
| Hydroxychloroquine Sulfate | 331-21357 | 747-36-4 | Malaria (endosome/ACE2) |
| Baricitinib Phosphate | 332-10769 | 1187595-84-1 | JAK kinase that regulate the inflammatory processes |
Multiplex Protein Array
Semi-quantitative detection of IgM and IgG antibodies in serum or plasma to the SARS-CoV-2 (COVID-19) spike (S) protein.
Questions? Please contact [email protected] or at (888) 494-8555.
References:
- Li, W. et al. (2003) Nature 426:450.
- Hoffmann, M. et al. (2020) Cell. DOI: 10.1016/j.cell.2020.02.052.
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RayBiotech Life, Inc.
3607 Parkway Lane Suite 200
Peachtree Corners, GA 30092
Tel: 770-729-2992, 1-888-494-8555 (toll-free)
Fax: 770-206-2393
Email: [email protected]
