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Explore comprehensive services and assay kits for sensitive, reproducible detection of RNA, DNA, and histone modifications. Build your own toolkit to generate robust data on the molecular mechanisms that drive health and disease.
In a 5-hour workflow, you can identify and profile gene-specific RNA methylation sites for m1A, m6A, m5C, and m7G, and DNA methylation sites for m5C. Each kit combines methylated RNA/DNA immunoprecipitation (MeRIP/MeDIP) with quantitative real-time PCR in a fast, streamlined procedure to identify the abundance and enrichment location of four common modifications.
Species: Human, Mouse, Rat
Sample Types: Extracted RNA
Achieve rapid, quantitative detection of 7 different RNA/DNA modifications: m1A, m6A, m7G, m5C, 5-hmC, ac4C, and A-to-I edits, using a standard microplate reader.
Targets: m1A, m6A, m5C, m7G, 5-hmC, ac4C, A-to-I
Species: Human, Mouse, Rat
Sample Types: Plasma, Serum, Urine
Now available: ready-made dot blot immunoassays for rapid detection of common global modifications, compatible with serum, plasma, or extracted RNA. Single-target assays support focused studies, while combination kits offer comprehensive profiling in one run, giving you the flexibility to match your research needs.
Targets: m1A, m6A, m5C, m7G, 5-hmC, ac4C, A-to-I, GlycoRNA, Pseudouridine
Species: Human, Mouse, Rat
Sample Types: Plasma*, Serum*, Extracted RNA
*Not validated for GlycoRNA, or Pseudouridine
Beyond nucleic acid modifications, RayBiotech's histone ELISAs detect the phosphorylation, acetylation, methylation, citrullination, and sumoylation marks that regulate chromatin structure and gene expression, alongside quantitative kits for the enzymes that write and erase them.
General purpose reagents and consumables for sample preparation and QC, commonly used alongside the epigenetics assays above to get from raw sample to assay-ready material.